Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2001-9-19
pubmed:abstractText
A prospective study was conducted to determine (i) the degree of yeast colonization in surgical patients with intra-abdominal perforations and (ii) whether the frequency of colonization is different in patients with a complicated postoperative course than in patients recovering uneventfully. A total of 1,496 specimens taken per- and post-operatively from the mouth, stomach, feces, urine, trachea, and abdomen of 109 surgical patients with intra-abdominal perforations were examined. Yeast was recovered from 98 (90%) of the patients and from 634 (42%) of the specimens. Approximately 70% of the specimens from the mouth and stomach, 47% of fecal specimens, and 31% of abdominal specimens were positive for yeast. A total of 42 patients had a complicated postoperative course. The majority of these patients were colonized with yeast at multiple body sites: yeast was recovered on one or more occasions from two or more body sites in 90% and from three or more body sites in 71%. Many of the patients with an uncomplicated postoperative course also were colonized: yeast was recovered from two or more body sites in 69% and from three or more body sites in 34%. The results of this study indicate that treatment recommendations based on yeast colonization will expose a large number of patients to unnecessary or even harmful antifungal treatment. This does not mean that yeast colonization is insignificant; however, more accurate criteria and methods based on prospective clinical studies are needed to detect patients at risk of developing severe Candida infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0934-9723
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
475-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:11561803-Adolescent, pubmed-meshheading:11561803-Adult, pubmed-meshheading:11561803-Aged, pubmed-meshheading:11561803-Aged, 80 and over, pubmed-meshheading:11561803-Antifungal Agents, pubmed-meshheading:11561803-Colony Count, Microbial, pubmed-meshheading:11561803-Female, pubmed-meshheading:11561803-Follow-Up Studies, pubmed-meshheading:11561803-Humans, pubmed-meshheading:11561803-Incidence, pubmed-meshheading:11561803-Intestinal Perforation, pubmed-meshheading:11561803-Male, pubmed-meshheading:11561803-Middle Aged, pubmed-meshheading:11561803-Mycoses, pubmed-meshheading:11561803-Postoperative Complications, pubmed-meshheading:11561803-Postoperative Period, pubmed-meshheading:11561803-Preoperative Care, pubmed-meshheading:11561803-Probability, pubmed-meshheading:11561803-Prospective Studies, pubmed-meshheading:11561803-Risk Factors, pubmed-meshheading:11561803-Survival Rate, pubmed-meshheading:11561803-Yeasts
pubmed:year
2001
pubmed:articleTitle
Yeast colonization in surgical patients with intra-abdominal perforations.
pubmed:affiliation
Department of Bacteriology, National Institute of Public Health, Oslo, Norway. per.sandven@folkehelsa.no
pubmed:publicationType
Journal Article, Comparative Study