Source:http://linkedlifedata.com/resource/pubmed/id/11561144
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
2001-9-18
|
pubmed:abstractText |
The lymphatic clearance of the human skin at the instep of the foot was measured in 20 healthy volunteers (mean age +/- SD 33.8 +/- 10.5 years). Ten microliters of fluorescein isothiocyanate-dextran 150,000 were injected intradermally and the fluorescent light intensity of the deposit was measured 10 min and 24 h after injection by window densitometry. Fluorescent light intensity decreased by 31.2 +/- 13.5 arbitrary units (p < 0.0001) or by a factor of 4.1 +/- 3.9. Reproducibility was tested 2-6 weeks later in 7 subjects and an intraclass reliability of 0.76 was found. These are the first measurements of the lymphatic clearance of the human skin using a fluorescent tracer. The method is easier and safer than the isotope clearance technique and small areas of the human skin can be investigated. The data found form a basis with which to compare measurements made in patients with different forms of edema.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1018-1172
|
pubmed:author | |
pubmed:copyrightInfo |
Copyright 2001 S. Karger AG, Basel
|
pubmed:issnType |
Print
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
423-31
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11561144-Adult,
pubmed-meshheading:11561144-Aged,
pubmed-meshheading:11561144-Dextrans,
pubmed-meshheading:11561144-Female,
pubmed-meshheading:11561144-Fluorescein-5-isothiocyanate,
pubmed-meshheading:11561144-Fluorescent Dyes,
pubmed-meshheading:11561144-Foot,
pubmed-meshheading:11561144-Humans,
pubmed-meshheading:11561144-Injections, Subcutaneous,
pubmed-meshheading:11561144-Kinetics,
pubmed-meshheading:11561144-Lymph,
pubmed-meshheading:11561144-Lymphatic System,
pubmed-meshheading:11561144-Lymphography,
pubmed-meshheading:11561144-Male,
pubmed-meshheading:11561144-Metabolic Clearance Rate,
pubmed-meshheading:11561144-Middle Aged,
pubmed-meshheading:11561144-Skin
|
pubmed:articleTitle |
Measurement of the lymphatic clearance of the human skin using a fluorescent tracer.
|
pubmed:affiliation |
Department of Internal Medicine, Angiology Division, University Hospital, Zürich, Switzerland.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|