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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2003-10-29
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pubmed:abstractText |
Phorbol 12-myristate 13-acetate (PMA) is often used as an activating phorbol ester of protein kinase C (PKC) to investigate the roles of the kinase in cellular functions. Accumulating lines of evidence indicate that in addition to activating PKC, PMA also produces some regulatory effects in a PKC-independent manner. In this study, we investigated the non-PKC effects of PMA on electrical excitability of rat pancreatic beta-cells by using patch-clamp techniques.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-10480603,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-10491749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-10580426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-11282458,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-1445368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-1706940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-1874734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-2018516,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-2459299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-2565041,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-2690820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-3056715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-3057214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-3281655,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-3304975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-6270629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-6429145,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-7531203,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-7737456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-7832756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-8074184,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-8300606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-8385120,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-8593703,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-8593708,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-8663368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-8781473,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-8843732,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-9056184,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-9144288,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-9486652,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-9831713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11560763-9950849
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2210
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11560763-ATP-Binding Cassette Transporters,
pubmed-meshheading:11560763-Animals,
pubmed-meshheading:11560763-Carcinogens,
pubmed-meshheading:11560763-Islets of Langerhans,
pubmed-meshheading:11560763-KATP Channels,
pubmed-meshheading:11560763-Male,
pubmed-meshheading:11560763-Phorbol Esters,
pubmed-meshheading:11560763-Potassium Channels,
pubmed-meshheading:11560763-Potassium Channels, Inwardly Rectifying,
pubmed-meshheading:11560763-Protein Kinase C,
pubmed-meshheading:11560763-Rats,
pubmed-meshheading:11560763-Rats, Wistar,
pubmed-meshheading:11560763-Tetradecanoylphorbol Acetate
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pubmed:year |
2001
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pubmed:articleTitle |
Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of KATP channels.
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pubmed:affiliation |
Department of Physiology, Hirosaki University School of Medicine, Hirosaki, 036-8562, Japan. ssuga@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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