Source:http://linkedlifedata.com/resource/pubmed/id/11557193
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2001-9-14
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pubmed:abstractText |
The regulatory cytokine transforming growth factor (TGF)-beta1 is thought to play a role in atherosclerotic heart disease as well as in idiopathic cardiomyopathy. The production of TGF-beta1 is genetically controlled as polymorphisms in the signaling sequence of the TGF-beta1 gene leucine(10)-->proline and arginine(25)-->proline are involved in the regulation of the protein production level. We investigated whether these polymorphisms are associated with end-stage heart failure caused by dilated cardiomyopathy (CMP) or ischemic heart disease (IHD).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1053-2498
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
979-84
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11557193-Adult,
pubmed-meshheading:11557193-Cardiomyopathy, Dilated,
pubmed-meshheading:11557193-Codon,
pubmed-meshheading:11557193-Female,
pubmed-meshheading:11557193-Genotype,
pubmed-meshheading:11557193-Heart Failure,
pubmed-meshheading:11557193-Humans,
pubmed-meshheading:11557193-Male,
pubmed-meshheading:11557193-Middle Aged,
pubmed-meshheading:11557193-Myocardial Ischemia,
pubmed-meshheading:11557193-Polymorphism, Genetic,
pubmed-meshheading:11557193-Sex Factors,
pubmed-meshheading:11557193-Transforming Growth Factor beta,
pubmed-meshheading:11557193-Transforming Growth Factor beta1
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pubmed:year |
2001
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pubmed:articleTitle |
TGF-beta1 gene polymorphisms in patients with end-stage heart failure.
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pubmed:affiliation |
Department of Internal Medicine, University Hospital Rotterdam-Dijkzigt, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. Holweg@inw1.azr.nl
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pubmed:publicationType |
Journal Article,
Comparative Study
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