| pubmed-article:11557063 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C0007589 | lld:lifeskim |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C0600432 | lld:lifeskim |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C0597298 | lld:lifeskim |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C0282498 | lld:lifeskim |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C1704259 | lld:lifeskim |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C1705987 | lld:lifeskim |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C1511938 | lld:lifeskim |
| pubmed-article:11557063 | lifeskim:mentions | umls-concept:C1516960 | lld:lifeskim |
| pubmed-article:11557063 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:11557063 | pubmed:dateCreated | 2001-9-14 | lld:pubmed |
| pubmed-article:11557063 | pubmed:abstractText | In this study we report the activation of c-Jun N-terminal kinase (JNK) in human K562 erythroleukemia cells undergoing hemin-mediated erythroid differentiation, which occurs concomitantly with activation of heat shock factor 2 (HSF2) and leads to a simultaneous in vivo phosphorylation of c-Jun. The activation of JNK occurs through activation of mitogen-activated protein kinase kinase (MKK) 4 and not by activation of MKK7 or inhibition of JNK-directed phosphatases. We have previously shown that overexpression of the HSF2-beta isoform inhibits the activation of HSF2 upon hemin-induced erythroid differentiation. Here we demonstrate that HSF2-beta overexpression blocks the hemin-induced activation of the MKK4-JNK pathway, suggesting an erythroid lineage-specific JNK activation likely to be regulated by HSF2. | lld:pubmed |
| pubmed-article:11557063 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11557063 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11557063 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11557063 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:11557063 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:11557063 | pubmed:author | pubmed-author:ElySS | lld:pubmed |
| pubmed-article:11557063 | pubmed:author | pubmed-author:ErikssonJ EJE | lld:pubmed |
| pubmed-article:11557063 | pubmed:author | pubmed-author:SistonenLL | lld:pubmed |
| pubmed-article:11557063 | pubmed:author | pubmed-author:KyriakisJ MJM | lld:pubmed |
| pubmed-article:11557063 | pubmed:author | pubmed-author:CoffeyE TET | lld:pubmed |
| pubmed-article:11557063 | pubmed:author | pubmed-author:HietakangasVV | lld:pubmed |
| pubmed-article:11557063 | pubmed:author | pubmed-author:RosenströmHH | lld:pubmed |
| pubmed-article:11557063 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11557063 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:11557063 | pubmed:volume | 505 | lld:pubmed |
| pubmed-article:11557063 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11557063 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11557063 | pubmed:pagination | 168-72 | lld:pubmed |
| pubmed-article:11557063 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:meshHeading | pubmed-meshheading:11557063... | lld:pubmed |
| pubmed-article:11557063 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11557063 | pubmed:articleTitle | Activation of the MKK4-JNK pathway during erythroid differentiation of K562 cells is inhibited by the heat shock factor 2-beta isoform. | lld:pubmed |
| pubmed-article:11557063 | pubmed:affiliation | Turku Centre for Biotechnology, University of Turku, Abo Akademi University, Finland. | lld:pubmed |
| pubmed-article:11557063 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11557063 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
