Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1975-11-5
pubmed:abstractText
The metabolism of colon smooth muscle from normal and alloxan-diabetic rabbits was studied in vitro. Glucose uptake, incorporation of glucose minus14-C into glycogen and incorporation of leucine minus-14C into protein were determined. These three parameters were all depressed in diabetic smooth muscle incubated in a medium containing 5.6 mM glucose. Raising the glucose concentration in the medium to 22.2 mM almost doubled the glucose uptake both in diabetic and normal smooth muscle and at this glucose concentration no significant difference in this parameter was found. Insulin (0.1 U/ml) added in vitro stimulated glucose uptake, incorporation of glucose minus14-C into glycogen and incorporation of leucine minus14-C into protein in diabetic colon smooth muscle. Insulin stimulated glucose uptake to the same degree in normal and diabetic colon smooth muscle, while its effect on glucose minus14-C and leucine minus14-C incorporation tended to be somewhat more pronounced in diabetic colon muscle.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0001-6772
pubmed:author
pubmed:issnType
Print
pubmed:volume
93
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
500-4
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Effect of alloxan-diabetes on the metabolism of rabbit colon smooth muscle.
pubmed:publicationType
Journal Article