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pubmed-article:11549872pubmed:abstractTextLittle information is available on the relevance of parameters representing the insulin-like growth factor (IGF) system with regard to growth hormone (GH) treatment during childhood. In adults, high IGF-I levels were found to be associated with side effects and long-term risks. AIM/METHOD: Our aim was to monitor the serum levels of IGF-I, IGF-binding protein (IGFBP) 3, and IGFBP-2 during long-term GH treatment of 156 patients with GH deficiency (GHD) and of 153 non-GHD patients. We determined the extent to which the IGF parameters exceed the normal ranges and identified those parameters which are predictive of 1st-year growth.lld:pubmed
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pubmed-article:11549872pubmed:authorpubmed-author:WeberKKlld:pubmed
pubmed-article:11549872pubmed:authorpubmed-author:RankeM BMBlld:pubmed
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pubmed-article:11549872pubmed:authorpubmed-author:WollmannH AHAlld:pubmed
pubmed-article:11549872pubmed:authorpubmed-author:ElmlingerM...lld:pubmed
pubmed-article:11549872pubmed:authorpubmed-author:SchwarzeC PCPlld:pubmed
pubmed-article:11549872pubmed:copyrightInfoCopyright 2001 S. Karger AG, Basellld:pubmed
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pubmed-article:11549872pubmed:volume55lld:pubmed
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pubmed-article:11549872pubmed:pagination115-24lld:pubmed
pubmed-article:11549872pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:11549872pubmed:year2001lld:pubmed
pubmed-article:11549872pubmed:articleTitleRelevance of IGF-I, IGFBP-3, and IGFBP-2 measurements during GH treatment of GH-deficient and non-GH-deficient children and adolescents.lld:pubmed
pubmed-article:11549872pubmed:affiliationPaediatric Endocrinology Section, University Children's Hospital, Hoppe-Seyler Strasse 1, D-72076 Tübingen, Germany. mlranke@med.uni-tuebingen.delld:pubmed
pubmed-article:11549872pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11549872pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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