|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2001-9-10
|
|
pubmed:abstractText |
Little information is available on the relevance of parameters representing the insulin-like growth factor (IGF) system with regard to growth hormone (GH) treatment during childhood. In adults, high IGF-I levels were found to be associated with side effects and long-term risks. AIM/METHOD: Our aim was to monitor the serum levels of IGF-I, IGF-binding protein (IGFBP) 3, and IGFBP-2 during long-term GH treatment of 156 patients with GH deficiency (GHD) and of 153 non-GHD patients. We determined the extent to which the IGF parameters exceed the normal ranges and identified those parameters which are predictive of 1st-year growth.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0301-0163
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright 2001 S. Karger AG, Basel
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
55
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
115-24
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:11549872-Adolescent,
pubmed-meshheading:11549872-Body Height,
pubmed-meshheading:11549872-Child,
pubmed-meshheading:11549872-Female,
pubmed-meshheading:11549872-Growth Disorders,
pubmed-meshheading:11549872-Growth Hormone,
pubmed-meshheading:11549872-Human Growth Hormone,
pubmed-meshheading:11549872-Humans,
pubmed-meshheading:11549872-Insulin-Like Growth Factor Binding Protein 2,
pubmed-meshheading:11549872-Insulin-Like Growth Factor Binding Protein 3,
pubmed-meshheading:11549872-Insulin-Like Growth Factor I,
pubmed-meshheading:11549872-Longitudinal Studies,
pubmed-meshheading:11549872-Male
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Relevance of IGF-I, IGFBP-3, and IGFBP-2 measurements during GH treatment of GH-deficient and non-GH-deficient children and adolescents.
|
|
pubmed:affiliation |
Paediatric Endocrinology Section, University Children's Hospital, Hoppe-Seyler Strasse 1, D-72076 Tübingen, Germany. mlranke@med.uni-tuebingen.de
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
