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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1975-11-7
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pubmed:abstractText |
A dynamic model for the structure of ribosomes is developed using X-ray small-angle scattering data and electron micrographs of ribosomes and polysomes. The large subunit has the shape of a conical frustum, and has a groove at its flat side. The small subunit consists of two semiparticles which are connected by a molecular strand; it may assume two conformations: a prolate P conformation and an oblate O conformation. Translocation of the ribosome along the mRNA in the elongation process of protein synthesis is accomplished by cyclic conformation transitions P-O-P-O in combination with the linking and rupturing of bonds. This mechanism is called "rack and roll" mechanism.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-5318
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
229-39
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1154947-Animals,
pubmed-meshheading:1154947-Binding Sites,
pubmed-meshheading:1154947-Microscopy, Electron,
pubmed-meshheading:1154947-Polyribosomes,
pubmed-meshheading:1154947-Protein Biosynthesis,
pubmed-meshheading:1154947-RNA, Messenger,
pubmed-meshheading:1154947-RNA, Ribosomal,
pubmed-meshheading:1154947-Rats,
pubmed-meshheading:1154947-Ribosomes
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pubmed:year |
1975
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pubmed:articleTitle |
[Structure of animal ribosomes. VI. Adynamic model of ribosome structure].
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pubmed:publicationType |
Journal Article,
English Abstract
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