11549452

Source:http://linkedlifedata.com/resource/pubmed/id/11549452

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0014834, umls-concept:C0033068, umls-concept:C1999216
pubmed:issue	18
pubmed:dateCreated	2001-9-10
pubmed:abstractText	To identify selective prephenate dehydratase (PDT) inhibitors, a series of substituted biphenic acid derivatives was synthesized using the Ullmann reaction. Screening experiments identified 18 as a promising new PDT inhibitor.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/GM 24054
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Chorismate Mutase, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Nitrobenzoates, http://linkedlifedata.com/resource/pubmed/chemical/Prephenate Dehydratase
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	0960-894X
pubmed:author	pubmed-author:ChenSS, pubmed-author:GanemBB, pubmed-author:HusainAA, pubmed-author:WilsonD BDB
pubmed:issnType	Print
pubmed:day	17
pubmed:volume	11
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2485-8
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:11549452-Chorismate Mutase, pubmed-meshheading:11549452-Drug Design, pubmed-meshheading:11549452-Drug Evaluation, Preclinical, pubmed-meshheading:11549452-Enzyme Inhibitors, pubmed-meshheading:11549452-Escherichia coli, pubmed-meshheading:11549452-Inhibitory Concentration 50, pubmed-meshheading:11549452-Nitrobenzoates, pubmed-meshheading:11549452-Prephenate Dehydratase, pubmed-meshheading:11549452-Structure-Activity Relationship
pubmed:year	2001
pubmed:articleTitle	A selective inhibitor of Escherichia coli prephenate dehydratase.
pubmed:affiliation	Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.