Source:http://linkedlifedata.com/resource/pubmed/id/11548201
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2001-9-7
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pubmed:abstractText |
The effects in vitro of tea tree oil (TTO) and plaunotol were examined by monitoring the growth of a standard strain of Staphylococcus aureus FDA 209P and of fourteen methicillin-susceptible strains of S. aureus (MSSA), together with twenty methicillin-resistant strains (MRSA). The minimum inhibitory concentrations (MIC) and the doses for 50% inhibition of growth (ID50) were determined by the micro-broth dilution (MD) method, and the broth dilution with shaking (BDS) method, respectively. The MIC of plaunotol for 50 and 90% of the MSSA and MRSA were assessed by the MD method, as 16 microg/ml and > or = 1,024 microg/ml, respectively. No antibacterial effects of TTO on MSSA and MRSA were detected by the MD method. The growth-inhibitory effects of TTO on S. aureus by the BDS method were examined, and it appeared that TTO was effective over a lower range of concentrations than previously reported. It seems that TTO is very effective in vitro against MSSA and MRSA at high concentrations but less effective below 40 microg/ml of TTO.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Alcohols,
http://linkedlifedata.com/resource/pubmed/chemical/Methicillin,
http://linkedlifedata.com/resource/pubmed/chemical/Oils, Volatile,
http://linkedlifedata.com/resource/pubmed/chemical/Penicillins,
http://linkedlifedata.com/resource/pubmed/chemical/Tea Tree Oil,
http://linkedlifedata.com/resource/pubmed/chemical/plaunotol
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pubmed:status |
MEDLINE
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pubmed:issn |
0026-2633
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
106 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11548201-Anti-Bacterial Agents,
pubmed-meshheading:11548201-Fatty Alcohols,
pubmed-meshheading:11548201-Humans,
pubmed-meshheading:11548201-Methicillin,
pubmed-meshheading:11548201-Methicillin Resistance,
pubmed-meshheading:11548201-Microbial Sensitivity Tests,
pubmed-meshheading:11548201-Oils, Volatile,
pubmed-meshheading:11548201-Penicillins,
pubmed-meshheading:11548201-Staphylococcus aureus,
pubmed-meshheading:11548201-Tea Tree Oil
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pubmed:year |
2001
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pubmed:articleTitle |
Comparison of the effects in vitro of tea tree oil and plaunotol on methicillin-susceptible and methicillin-resistant strains of Staphylococcus aureus.
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pubmed:affiliation |
Department of Microbiology, Showa Pharmaceutical University, Machida, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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