Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-9-6
pubmed:abstractText
The results of pharmacogenetic experiments revealed specificity of the emotional-stress reactions (ESR) in the inherited deterministic type of behavior and showed dependence of the benzodiazepine tranquilizer action on the ESR phenotype. Based on these data, we carried out experiments with a group of volunteers performing operator functions in a model of emotional-stress conditions. The results of these experiments allowed the operators to be divided into stress-resistant and stress-affected groups. The results of the data processing by methods of multidimensional statistics showed possibility of predicting the ESR phenotype and the qualitative effect of phenazepam (0.5 mg. p.o.) based on the individual topological and hormonal-biochemical characteristics of operators.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0869-2092
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3-12
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
[Predicting individual reactions to emotional stress and benzodiazepine tranquilizers].
pubmed:affiliation
Laboratory of Pharmacogenetics, Institute of Pharmacology, Russian Academy of Medical Sciences, Baltiiskaya ul. 8, Moscow, 125315 Russia.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract