Linked Life Data

11542706

Source:http://linkedlifedata.com/resource/pubmed/id/11542706

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-4-2
pubmed:abstractText
Objective To investigate variations of plasma renin activity, a prostaglandin I2 (PGI2) during 21 d -6 degrees head-down tilt (HDT) with and without lower body negative pressure (LBNP). METHOD: -6 degrees head-down tilt for 21 d were used to simulate weightlessness. 12 healthy male, aged 23.7 +/- 5.0, were equally and randomly divided into control group (CON) and LBNP group. The latter subjected to LBNP (-30 mm Hg, 1 h/d) in the last week of HDT. Samples of plasma were taken before HDT and on the 2nd, 4th, 11th and 22nd day during HDT. RESULT: Compare to control levels, Ald declined significantly on the 2nd (CON -30%, P < 0. 05; V. S. LBNP -38%, P < 0.01), and increased significantly on the 11th day (CON +30%, P < 0.05; LBNP +48%, P < 0.01). PRA reached peak value on the 4th day (P < 0.05), and declined to below the control level on the 22nd day. PGI2 increased constantly during HDT, and increased significantly on the 22nd day (CON P < 0.01), 11th, 22nd (LBNP P < 0.05). No apparent difference was found between groups after LBNP concerning PRA and Ald; and PGI2 didn't increase further in LBNP group. Conclusion HDT induced a timely increasing in PRA and Ald, constant increasing in PGI2.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
S
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1002-0837
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NASA
pubmed:authorsComplete
Y
pubmed:pagination
258-61
pubmed:dateRevised
2010-3-24
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
[Variation of several volume regulating hormones during 21 d - 6 degrees head-down bed rest].
pubmed:affiliation
Department of Aviation Medicine, The Fourth Military Medical University, Xi'an, China.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, English Abstract, Randomized Controlled Trial