Linked Life Data

1153941

Source:http://linkedlifedata.com/resource/pubmed/id/1153941

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1975-11-6
pubmed:abstractText
Human gallbladder epithelium was disintegrated to complete loss of microscopic structure. The material obtained - an extract - was incubated at 37 degrees C together with a mixture of lecithin and lysolecithin, phospholipids known to be present in bile. During such incubation a change in the phospholipid composition occurred, indicating that lecithin was converted to lysolechitin. This conversion increased in the presence of CaCl2. Heating the disintegrated epithelium (70 degrees C for 10 min at pH 4) considerably increased the phospholipid conversion. The results are consistent with the presence of phospholipase A activity in human gallbladder epithelium. The possible significance of this activity is discussed in view of the inflammation-mediating activity of lysolecithin in the gallbladder epithelium.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0036-5521
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
459-63
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
The prerequisites for local lysolecithin formation in the human gallbladder.
pubmed:publicationType
Journal Article