Linked Life Data

11538245

Source:http://linkedlifedata.com/resource/pubmed/id/11538245

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Suppl
pubmed:dateCreated
1996-10-7
pubmed:abstractText
This work is a continuation of efforts to assess responses of rat skeletal muscle to weightlessness and earthside laboratory experiments with unloading of hind limbs. The soleus is a slow twitch, load bearing (antigravity) muscle. Both exposure to weightlessness (W) and to the hypokinesia/hypodynamia of whole body suspension (WBS) results in soleus atrophy. Cross sectional areas of both slow and fast twitch fibers decrease during 7 days of W, and 7 or 14 days of WBS. Density and area changes tended to reverse to control levels during 7 days of recovery (R) following WBS. Capillary density was increased with 7 days of W, and 7 or 14 days of WBS. During 7 days of R the capillary density returned toward control levels. In summary, the reduction in fiber cross sectional areas and increase in fiber and capillary densities support the hypothesis that in both forms of disuse, i.e., W and WBS, there is a loss in soleus muscle cell mass and not in fiber numbers.
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
S
pubmed:status
MEDLINE
pubmed:issn
0031-9376
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NASA
pubmed:authorsComplete
Y
pubmed:pagination
S28-9
pubmed:dateRevised
2007-8-1
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Comparative morphometry of fibers and capillaries in soleus following weightlessness (SL-3) and suspension.
pubmed:affiliation
Dept. Physiology, University of Louisville, KY 40292, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.