Linked Life Data

11529314

Source:http://linkedlifedata.com/resource/pubmed/id/11529314

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2001-8-31
pubmed:abstractText
Diffuse feedback is defined to be a process by which a system in some sense improves its performance with respect to a variety of conflicting and even contradictory goals. In the immune system, such feedback is mediated by scores of extracellular chemicals (cytokines), each of which participates in achieving several goals. Progress toward any given goal is mediated by several cytokines. The 'immunoinformatics' of this diffuse informational network will be discussed. It will be shown how diffuse feedbacks, based on this network, can improve the performance of a given type of immune effector cell, and can cause the preferential amplification of more potent effectors. It will be argued that diffuse feedback also acts in other biological systems ranging from the metabolic system to ant colonies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1528-2511
pubmed:author
pubmed:issnType
Print
pubmed:volume
239
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-40; discussion 40-51
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Controlling the immune system: diffuse feedback via a diffuse informational network.
pubmed:affiliation
Department of Computer Science and Applied Mathematics, The Weizmann Institute of Science, Rehovot, Israel.
pubmed:publicationType
Journal Article, Review