Swim-up techniques for sperm separation may have detrimental effects on sperm DNA. We wished to determine whether the normal swim-up method with centrifugation used in our laboratory, which involves a centrifugation step, was harmful to sperm compared with swim-up without centrifugation.
Division of Reproductive Sciences, The Toronto General Hospital, The Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Ontario, Canada. younglai@mcmaster.ca