Source:http://linkedlifedata.com/resource/pubmed/id/11527740
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
17
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pubmed:dateCreated |
2001-8-30
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pubmed:abstractText |
The synthesis and biological activities of a series of new 1beta-methylcarbapenems 1a-h having heteroaromatic thioether moiety at C-5 position of pyrrolidine were described. Among these compounds, 1,2,3-thiadiazole derivative 1h showed the most potent antibacterial activity and advanced pharmacokinetics in comparison with meropenem.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2397-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11527740-Animals,
pubmed-meshheading:11527740-Anti-Infective Agents,
pubmed-meshheading:11527740-Area Under Curve,
pubmed-meshheading:11527740-Carbapenems,
pubmed-meshheading:11527740-Drug Design,
pubmed-meshheading:11527740-Drug Evaluation, Preclinical,
pubmed-meshheading:11527740-Microbial Sensitivity Tests,
pubmed-meshheading:11527740-Rats,
pubmed-meshheading:11527740-Thienamycins
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pubmed:year |
2001
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pubmed:articleTitle |
Synthesis and biological properties of new 1beta-methylcarbapenems containing heteroaromatic thioether moiety.
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pubmed:affiliation |
Medicinal Chemistry Research Center, Korea Institute of Science and Technology, Seoul 130-650, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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