Linked Life Data

11526850

Source:http://linkedlifedata.com/resource/pubmed/id/11526850

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2001-8-30
pubmed:abstractText
Exploration of the cytoplasm of the giant esophageal cell of Ascaris with a recording microelectrode shows the existence of shallow spaces where the microelectrode tip becomes extracellular in spite of being in the interior of the cell. When the microelectrode penetrates into these spaces from the cytoplasm, the resting potential shifts to a different level or entirely disappears. At the same time the large intracellular spikes are replaced by small transients similar to extracellularly recorded action potentials. It is concluded that such spaces are in communication with the external solution, and separated from the cytoplasm by an electrically active membrane; i.e., able to generate action potentials. Measurement of the potential differences between the interior of the spaces and the external solution shows that although some are not polarized, many spaces have a resting potential of the same polarity as that of the cytoplasm. It is suggested that although they are of larger size these spaces may be equivalent to the tubular systems which in other muscle cells are known to be involved in the spread of excitation into the cytoplasm.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0022-1295
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
631-45
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1967
pubmed:articleTitle
Extracellular action potentials recorded from the interior of the giant esophageal cell of Ascaris.
pubmed:affiliation
Department of Pharmacology, School of Medicine, San Juan, Puerto Rico.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.