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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2001-8-29
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pubmed:databankReference |
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pubmed:abstractText |
The plant hormone abscisic acid (ABA) regulates important stress and developmental responses. We have isolated a recessive ABA hypersensitive mutant, abh1, that shows hormone specificity to ABA. ABH1 encodes the Arabidopsis homolog of a nuclear mRNA cap binding protein and functions in a heterodimeric complex to bind the mRNA cap structure. DNA chip analyses show that only a few transcripts are down-regulated in abh1, several of which are implicated in ABA signaling. Consistent with these results, abh1 plants show ABA-hypersensitive stomatal closing and reduced wilting during drought. Interestingly, ABA-hypersensitive cytosolic calcium increases in abh1 guard cells demonstrate amplification of early ABA signaling. Thus, ABH1 represents a modulator of ABA signaling proposed to function by transcript alteration of early ABA signaling elements.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0092-8674
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
24
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
477-87
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11525733-Abscisic Acid,
pubmed-meshheading:11525733-Arabidopsis,
pubmed-meshheading:11525733-Arabidopsis Proteins,
pubmed-meshheading:11525733-Blotting, Northern,
pubmed-meshheading:11525733-Calcium,
pubmed-meshheading:11525733-Epistasis, Genetic,
pubmed-meshheading:11525733-Genes, Reporter,
pubmed-meshheading:11525733-Humans,
pubmed-meshheading:11525733-Molecular Sequence Data,
pubmed-meshheading:11525733-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:11525733-Plant Growth Regulators,
pubmed-meshheading:11525733-RNA Cap-Binding Proteins,
pubmed-meshheading:11525733-RNA Caps,
pubmed-meshheading:11525733-RNA-Binding Proteins,
pubmed-meshheading:11525733-Recombinant Fusion Proteins,
pubmed-meshheading:11525733-Seeds,
pubmed-meshheading:11525733-Signal Transduction,
pubmed-meshheading:11525733-Two-Hybrid System Techniques
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pubmed:year |
2001
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pubmed:articleTitle |
An mRNA cap binding protein, ABH1, modulates early abscisic acid signal transduction in Arabidopsis.
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pubmed:affiliation |
Division of Biology, Cell and Developmental Biology Section, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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