Source:http://linkedlifedata.com/resource/pubmed/id/11523947
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2001-8-28
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pubmed:abstractText |
Neurofibromatosis type 1 could be associated with multiple gastrointestinal stromal tumours, although their presence is not considered among the major diagnostic criteria. We present here a case of a 50-year-old female complaining of abdominal pain, with about 100 small intestinal stromal tumours. This finding prompted us to suspect a neurofibromatosis which was clinically confirmed afterwards. Light microscopy examination revealed a low-grade stromal tumour with skeinoid fibres. Mixed neural-interstitial cells of Cajal origin or, alternatively, neural differentiation of interstitial cells of Cajal are discussed on the basis of immunophenotype (CD117+, CD34+) and ultrastructure. A 2-year follow-up did not indicate an aggressive course in the case of this neoplasm.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0031-3025
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
390-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11523947-Antigens, CD34,
pubmed-meshheading:11523947-Digestive System,
pubmed-meshheading:11523947-Female,
pubmed-meshheading:11523947-Humans,
pubmed-meshheading:11523947-Immunophenotyping,
pubmed-meshheading:11523947-Intestinal Neoplasms,
pubmed-meshheading:11523947-Microscopy, Electron,
pubmed-meshheading:11523947-Middle Aged,
pubmed-meshheading:11523947-Muscle, Smooth,
pubmed-meshheading:11523947-Myenteric Plexus,
pubmed-meshheading:11523947-Neurofibromatosis 1,
pubmed-meshheading:11523947-Proto-Oncogene Proteins c-kit,
pubmed-meshheading:11523947-Tumor Markers, Biological
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pubmed:year |
2001
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pubmed:articleTitle |
Multiple small intestinal stromal tumours in a patient with previously unrecognised neurofibromatosis type 1: immunohistochemical and ultrastructural evaluation.
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pubmed:affiliation |
Dipartimento di Scienze Mediche Facoltà di Medicina e Chirurgia, Università Amedeo Avogadro del Piemonte Orientale, Novara, Italy. anapatol@starnova.it
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pubmed:publicationType |
Journal Article,
Case Reports
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