rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2001-8-27
|
pubmed:abstractText |
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is caused by mutations of both copies of the autoimmune regulator (AIRE) gene. It is characterized by susceptibility to mucocutaneous candidiasis and multiple autoimmune lesions. A serious disease component is hepatitis. To identify diagnostic autoantibodies for APECED hepatitis, sera from 64 patients with APECED were screened for autoantibodies established in the diagnosis of idiopathic autoimmune hepatitis, and for autoantibodies against 10 cytochrome P450s.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0016-5085
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
121
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
668-77
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11522751-Adolescent,
pubmed-meshheading:11522751-Adult,
pubmed-meshheading:11522751-Aged,
pubmed-meshheading:11522751-Autoantibodies,
pubmed-meshheading:11522751-Autoantigens,
pubmed-meshheading:11522751-Biological Markers,
pubmed-meshheading:11522751-Child,
pubmed-meshheading:11522751-Female,
pubmed-meshheading:11522751-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:11522751-Hepatitis,
pubmed-meshheading:11522751-Humans,
pubmed-meshheading:11522751-Liver,
pubmed-meshheading:11522751-Male,
pubmed-meshheading:11522751-Mass Screening,
pubmed-meshheading:11522751-Middle Aged,
pubmed-meshheading:11522751-Polyendocrinopathies, Autoimmune,
pubmed-meshheading:11522751-Recombinant Proteins
|
pubmed:year |
2001
|
pubmed:articleTitle |
Hepatic autoantigens in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.
|
pubmed:affiliation |
Department of Gastroenterology and Hepatology, Hanover Medical School, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|