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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2001-8-27
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pubmed:abstractText |
We have previously shown that aberrant crypt foci (ACF) are the putative precursor lesions of colorectal adenomas and subsequent cancer in humans using magnifying endoscopy. The present study was designed to investigate these genetic alterations in ACF biopsy specimens from normal subjects, familial adenomatous polyposis (FAP) or sporadic patients.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:HayashiTT,
pubmed-author:KatzGG,
pubmed-author:MiyanishiKK,
pubmed-author:NakajimaTT,
pubmed-author:NiitsuYY,
pubmed-author:NobuokaAA,
pubmed-author:OhiMM,
pubmed-author:SakamakiSS,
pubmed-author:SatohTT,
pubmed-author:TakayamaTT,
pubmed-author:TakimotoRR
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pubmed:issnType |
Print
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pubmed:volume |
121
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
599-611
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11522744-Adenomatous Polyposis Coli,
pubmed-meshheading:11522744-Adenomatous Polyposis Coli Protein,
pubmed-meshheading:11522744-Adult,
pubmed-meshheading:11522744-Aged,
pubmed-meshheading:11522744-Biopsy,
pubmed-meshheading:11522744-Colorectal Neoplasms,
pubmed-meshheading:11522744-Cytoskeletal Proteins,
pubmed-meshheading:11522744-Disease Progression,
pubmed-meshheading:11522744-Endoscopy, Gastrointestinal,
pubmed-meshheading:11522744-Female,
pubmed-meshheading:11522744-Genes, ras,
pubmed-meshheading:11522744-Genetic Testing,
pubmed-meshheading:11522744-Humans,
pubmed-meshheading:11522744-Immunohistochemistry,
pubmed-meshheading:11522744-Intestinal Mucosa,
pubmed-meshheading:11522744-Male,
pubmed-meshheading:11522744-Middle Aged,
pubmed-meshheading:11522744-Mutation,
pubmed-meshheading:11522744-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:11522744-Trans-Activators,
pubmed-meshheading:11522744-beta Catenin
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pubmed:year |
2001
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pubmed:articleTitle |
Analysis of K-ras, APC, and beta-catenin in aberrant crypt foci in sporadic adenoma, cancer, and familial adenomatous polyposis.
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pubmed:affiliation |
Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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