Source:http://linkedlifedata.com/resource/pubmed/id/11521786
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2001-8-27
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pubmed:abstractText |
We describe a case of locally advanced unresectable squamous-cell carcinoma of the oropharynx in a young woman with Bloom's syndrome. She was treated with radical radiation therapy and concurrent chemotherapy (cisplatin and 5-flurouracil). She was unable to complete treatment due to the development of severe side effects: confluent mucositis, moist desquamating skin reaction, severe diarrhea and severe myelosupression with neutropenic sepsis. The limited relevant literature is presented. We conclude that chemotherapy should be used with extreme caution in Bloom's syndrome patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0923-7534
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1015-7
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:11521786-Adult,
pubmed-meshheading:11521786-Antimetabolites, Antineoplastic,
pubmed-meshheading:11521786-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:11521786-Bloom Syndrome,
pubmed-meshheading:11521786-Carcinoma, Squamous Cell,
pubmed-meshheading:11521786-Chemotherapy, Adjuvant,
pubmed-meshheading:11521786-Cisplatin,
pubmed-meshheading:11521786-Female,
pubmed-meshheading:11521786-Fluorouracil,
pubmed-meshheading:11521786-Humans,
pubmed-meshheading:11521786-Neoplasm Invasiveness,
pubmed-meshheading:11521786-Oropharyngeal Neoplasms,
pubmed-meshheading:11521786-Radiotherapy, Adjuvant
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pubmed:year |
2001
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pubmed:articleTitle |
Combined modality treatment for locally advanced squamous-cell carcinoma of the oropharynx in a woman with Bloom's syndrome: a case report and review of the literature.
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pubmed:affiliation |
Division of Medical Oncology, Petcr MacCallum Cancer Institute, Melbourne, Victoria, Australia.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
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