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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1975-11-8
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pubmed:abstractText |
1. Foetal and maternal plasma catecholamine concentrations were measured during and after hypoxia (mean maternal Pa,02 44mmHg) in chronically catheterized sheep, 118-141 days pregnant. 2. In most foetuses the initial plasma catecholamines were smaller than 0.07 ng/ml. During hypoxia plasma adrenaline and noradrenaline always rose; there was a rise in arterial pressure and a fall in heart rate. 3. The initial catecholamine concentration in the ewes was smaller than 0.05-2.3 ng/ml. During hypoxia there was no consistent change; the maternal plasma concentrations were less than the foetal. 4. Infusion of adrenaline at 0.3 mug kg(-1) min(-1) to the ewe resulted in plasma catecholamine concentrations higher than those observed during hypoxia. There was a rise in heart rate but no consistent change in arterial pressure. 5. Infusion of adrenaline 0.4 mug kg(-1) min(-1) into the foetal jugular vein caused a rise in plasma concentration similar to that seen during hypoxia. There was a rise in heart rate but no significant change in arterial pressure. 6. The half-life of adrenaline and of noradrenaline in the maternal and foetal circulation was 0.25-1 min. There was no evidence of transfer of labelled catecholamine across the placenta.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-13377317,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-13377318,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-13481061,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-13866156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-13906919,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-14144417,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-14170146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-14221225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-14298116,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-15393454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-16747850,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-16994930,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-18884362,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4295757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4311889,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4333251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4333826,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4349454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4398020,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4404656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4487968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4664574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4697169,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4903077,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4952710,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4953059,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-4992588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-5020986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-5060378,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-5493883,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-5636505,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-5643948,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-5661936,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-5717548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-5773544,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-5904149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-6034176,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1151803-6048011
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-3751
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
248
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-33
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:1151803-Animals,
pubmed-meshheading:1151803-Anoxia,
pubmed-meshheading:1151803-Blood Pressure,
pubmed-meshheading:1151803-Catecholamines,
pubmed-meshheading:1151803-Epinephrine,
pubmed-meshheading:1151803-Female,
pubmed-meshheading:1151803-Fetal Blood,
pubmed-meshheading:1151803-Fetus,
pubmed-meshheading:1151803-Heart Rate,
pubmed-meshheading:1151803-Infusions, Parenteral,
pubmed-meshheading:1151803-Metabolic Clearance Rate,
pubmed-meshheading:1151803-Norepinephrine,
pubmed-meshheading:1151803-Pregnancy,
pubmed-meshheading:1151803-Sheep
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pubmed:year |
1975
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pubmed:articleTitle |
Plasma catecholamines in foetal and adult sheep.
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pubmed:publicationType |
Journal Article
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