Source:http://linkedlifedata.com/resource/pubmed/id/11512049
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2001-8-20
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pubmed:abstractText |
At high doses, methamphetamine produces repetitive stereotypic behaviors, and the degree to which this occurs is heritable. Objectives: Mice of a B6D2F2 genetic background were selectively bred for four generations for high (HMA) and low (LMA) numbers of stereotyped chewing episodes measured for 1 min at 33 min post-injection following 10 mg/kg methamphetamine (changed to 7 mg/kg for the high line and 15 mg/kg for the low line in the third selected generation to avoid ceiling and floor effects, respectively). We sought to determine whether stereotypic behaviors other than number of repetitive chewing episodes were altered by the selective breeding process.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0033-3158
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
157
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
96-104
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11512049-Alleles,
pubmed-meshheading:11512049-Animals,
pubmed-meshheading:11512049-Breeding,
pubmed-meshheading:11512049-Dose-Response Relationship, Drug,
pubmed-meshheading:11512049-Genotype,
pubmed-meshheading:11512049-Mastication,
pubmed-meshheading:11512049-Methamphetamine,
pubmed-meshheading:11512049-Mice,
pubmed-meshheading:11512049-Mice, Inbred C57BL,
pubmed-meshheading:11512049-Mice, Inbred DBA,
pubmed-meshheading:11512049-Stereotyped Behavior
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pubmed:year |
2001
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pubmed:articleTitle |
Stereotypic behaviors in mice selectively bred for high and low methamphetamine-induced stereotypic chewing.
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pubmed:affiliation |
Department of Behavioral Neuroscience, Oregon Health & Sciences University, 3710 SW US Veterans Hospital Road, R & D5, Portland, OR 97201, USA. atkinsa@ohsu.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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