rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2001-8-20
|
pubmed:abstractText |
CYFRA 21-1 is a newly developed tumor marker that is especially useful for detecting squamous cell carcinoma (SCC) of the lung. Squamous cell carcinoma antigen is a proven tumor marker that is especially useful for detecting SCC of the cervix. Our aim in this study was to compare the clinical value of CYFRA 21-1 and SCC antigen in the detection of nasopharyngeal carcinoma (NPC). Serum levels of CYFRA 21-1 and SCC antigen were measured in 80 untreated NPC patients and 77 healthy controls. The cutoff values of CYFRA 21-1 and SCC antigen, determined at the 95th percentile of the 77 healthy controls, were 2.48 ng/mL and 1.49 ng/mL, respectively. The results revealed that the mean serum value of only CYFRA 21-1 was significantly higher in the 80 NPC patients than in the 77 healthy controls, and the detection sensitivity of CYFRA 21-1 for NPC was significantly higher than that of SCC antigen. In conclusion, our results suggest that CYFRA 21-1 is a better tumor marker than SCC antigen for detection of NPC.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0003-4894
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
110
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
775-8
|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11510737-Adult,
pubmed-meshheading:11510737-Aged,
pubmed-meshheading:11510737-Aged, 80 and over,
pubmed-meshheading:11510737-Antigens, Neoplasm,
pubmed-meshheading:11510737-Carcinoma,
pubmed-meshheading:11510737-Carcinoma, Squamous Cell,
pubmed-meshheading:11510737-Female,
pubmed-meshheading:11510737-Humans,
pubmed-meshheading:11510737-Keratin-19,
pubmed-meshheading:11510737-Keratins,
pubmed-meshheading:11510737-Male,
pubmed-meshheading:11510737-Middle Aged,
pubmed-meshheading:11510737-Nasopharyngeal Neoplasms,
pubmed-meshheading:11510737-Sensitivity and Specificity,
pubmed-meshheading:11510737-Serpins,
pubmed-meshheading:11510737-Tumor Markers, Biological
|
pubmed:year |
2001
|
pubmed:articleTitle |
Comparison of CYFRA 21-1 and squamous cell carcinoma antigen in detecting nasopharyngeal carcinoma.
|
pubmed:affiliation |
Department of Nuclear Medicine, China Medical College Hospital, Taichung, Taiwan.
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pubmed:publicationType |
Journal Article
|