Source:http://linkedlifedata.com/resource/pubmed/id/11504627
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2001-8-15
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pubmed:abstractText |
A protective mechanism used by cells to adapt to stress of the endoplasmic reticulum (ER) is the induction of members of the glucose-regulated protein (Grp) family. The induction of mammalian Grp proteins in response to ER stress involves a complex network of regulators and novel mechanisms. The elucidation of Grp function and regulation opens up new therapeutic approaches to diseases associated with ER stress and cancer.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0968-0004
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
504-10
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11504627-Animals,
pubmed-meshheading:11504627-Gene Expression Regulation,
pubmed-meshheading:11504627-Gene Therapy,
pubmed-meshheading:11504627-HSP70 Heat-Shock Proteins,
pubmed-meshheading:11504627-Humans,
pubmed-meshheading:11504627-Immunotherapy,
pubmed-meshheading:11504627-Membrane Proteins,
pubmed-meshheading:11504627-Neoplasms,
pubmed-meshheading:11504627-Oxidative Stress,
pubmed-meshheading:11504627-Promoter Regions, Genetic,
pubmed-meshheading:11504627-Transcription, Genetic
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pubmed:year |
2001
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pubmed:articleTitle |
The glucose-regulated proteins: stress induction and clinical applications.
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pubmed:affiliation |
University of Southern California/Norris Comprehensive Cancer Center, Dept of Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089-9176, USA. amylee@hsc.usc.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review
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