Linked Life Data

11497866

Source:http://linkedlifedata.com/resource/pubmed/id/11497866

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2001-8-10
pubmed:abstractText
A genetic switch may be realized by a certain operator sector on the DNA strand from which either genetic code, to the left or to the right of this operator sector, can be transcribed and the corresponding information processed. This switch is controlled by messenger molecules, i.e., they determine to which side the switch is flipped. Recently, it has been realized that noise plays an elementary role in genetic switching, and the effect of number fluctuations of the messenger molecules have been explored. Here we argue that the assumption of well stirredness taken in the previous models may not be sufficient to characterize the influence of noise: spatial fluctuations play a non-negligible part in cellular genetic switching processes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0031-9007
pubmed:author
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
068103
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
The future is noisy: the role of spatial fluctuations in genetic switching.
pubmed:affiliation
Department of Physics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Rm 12-109, Cambridge, Massachusetts 02139, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't