11497275

Source:http://linkedlifedata.com/resource/pubmed/id/11497275

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001721, umls-concept:C0012899, umls-concept:C0032712, umls-concept:C0043393, umls-concept:C0441712, umls-concept:C0871261, umls-concept:C1155299, umls-concept:C1515926, umls-concept:C1704632, umls-concept:C1706817, umls-concept:C2911692
pubmed:issue	3B
pubmed:dateCreated	2001-8-10
pubmed:abstractText	DNA quadruplex-interactive porphyrin TMPyP4, but not its isomer TMPyP2, inhibits telomerase activity and causes chromosome fusion in vivo, suggesting interference with telomere maintenance.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/CA67760
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8102988
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyurea, http://linkedlifedata.com/resource/pubmed/chemical/Porphyrins
pubmed:status	MEDLINE
pubmed:issn	0250-7005
pubmed:author	pubmed-author:BarnesL DLD, pubmed-author:DavidsonK KKK, pubmed-author:HannibalG TGT, pubmed-author:IzbickiMM, pubmed-author:LawrenceR ARA, pubmed-author:RobinsonA KAK
pubmed:issnType	Print
pubmed:volume	21
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1899-903
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:11497275-Antineoplastic Agents, pubmed-meshheading:11497275-DNA Repair, pubmed-meshheading:11497275-Dose-Response Relationship, Drug, pubmed-meshheading:11497275-Hydroxyurea, pubmed-meshheading:11497275-Porphyrins, pubmed-meshheading:11497275-Saccharomyces cerevisiae, pubmed-meshheading:11497275-Telomere
pubmed:articleTitle	Alterations in DNA repair and telomere maintenance mechanism affect response to porphyrins in yeast.
pubmed:affiliation	Institute for Drug Development, CTRC, San Antonio TX 78245, USA. eizbicka@saci.org
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't