Source:http://linkedlifedata.com/resource/pubmed/id/11497016
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2001-8-10
|
| pubmed:abstractText |
Fanconi's anemia (FA) is an autosomal-recessive disorder characterized by a progressive pancytopenia, diverse congenital abnormalities and increased predisposition to malignancy. Sixteen children with FA, aged between 4 to 16 were divided into two groups according to treatments. Nine children had bone marrow transplantation and seven children were treated with steroid and/or anapolan. The changes in dental caries, caries-associated microflora, salivary status and periodontal health were investigated in children with FA. Data were analyzed by one-way ANOVA. A statistically significant difference was found in hematological findings between children who have received bone marrow transplantation (BMT+) and the others, who have not received (BMT-). There was no significant difference in dental caries experience, salivary flow rate, buffering capacity, mutans streptococci and Lactobacilli levels between the study groups. A statistically significant difference was found in gingival index, plaque index, bleeding on probing, probing depth scores between the patients with FA in BMT(+) and BMT(-) groups (p<.05). In conclusion, besides systemic control, additional preventive measures during their whole life to maintain oral health is necessary in these children.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
D
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1053-4628
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
329-32
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:11497016-Adolescent,
pubmed-meshheading:11497016-Analysis of Variance,
pubmed-meshheading:11497016-Bone Marrow Transplantation,
pubmed-meshheading:11497016-Child,
pubmed-meshheading:11497016-Child, Preschool,
pubmed-meshheading:11497016-Colony Count, Microbial,
pubmed-meshheading:11497016-DMF Index,
pubmed-meshheading:11497016-Dental Caries,
pubmed-meshheading:11497016-Dental Plaque,
pubmed-meshheading:11497016-Dental Plaque Index,
pubmed-meshheading:11497016-Fanconi Anemia,
pubmed-meshheading:11497016-Female,
pubmed-meshheading:11497016-Humans,
pubmed-meshheading:11497016-Lactobacillus,
pubmed-meshheading:11497016-Male,
pubmed-meshheading:11497016-Oral Health,
pubmed-meshheading:11497016-Periodontal Diseases,
pubmed-meshheading:11497016-Periodontal Index,
pubmed-meshheading:11497016-Saliva,
pubmed-meshheading:11497016-Secretory Rate,
pubmed-meshheading:11497016-Streptococcus mutans
|
| pubmed:year |
2001
|
| pubmed:articleTitle |
The effect of bone marrow transplantation on systemic and oral health in Fanconi's aplastic anemia.
|
| pubmed:affiliation |
Department of Pediatric Hematology, Oncology, Istanbul University, Faculty of Medicine, Turkey.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|