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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0059409,
umls-concept:C0185117,
umls-concept:C0950373,
umls-concept:C1312650,
umls-concept:C1334043,
umls-concept:C1880022,
umls-concept:C1998793,
umls-concept:C2911684
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pubmed:issue |
3
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pubmed:dateCreated |
2001-8-7
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pubmed:databankReference |
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pubmed:abstractText |
Human eosinophils contain two eosinophil ribonucleases, eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN). In rats, 8 homologues of human ECP and EDN have been identified. To clarify the biological activity of rat eosinophil ribonucleases, we cloned rat eosinophil-associated ribonuclease (EAR)-1/rat ribonuclease 7 and rat EAR-2/rat ribonuclease 4, and produced recombinant rat pre-EAR-1 and pre-EAR-2 in a bacterial expression system.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1018-2438
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2001 S. Karger AG, Basel.
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pubmed:issnType |
Print
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pubmed:volume |
125
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11490157-Amino Acid Sequence,
pubmed-meshheading:11490157-Animals,
pubmed-meshheading:11490157-Base Sequence,
pubmed-meshheading:11490157-Blood Bactericidal Activity,
pubmed-meshheading:11490157-Blood Proteins,
pubmed-meshheading:11490157-DNA, Complementary,
pubmed-meshheading:11490157-Eosinophil Granule Proteins,
pubmed-meshheading:11490157-Eosinophils,
pubmed-meshheading:11490157-Escherichia coli,
pubmed-meshheading:11490157-Genetic Vectors,
pubmed-meshheading:11490157-Humans,
pubmed-meshheading:11490157-Male,
pubmed-meshheading:11490157-Molecular Sequence Data,
pubmed-meshheading:11490157-Protein Precursors,
pubmed-meshheading:11490157-Rats,
pubmed-meshheading:11490157-Rats, Sprague-Dawley,
pubmed-meshheading:11490157-Recombinant Proteins,
pubmed-meshheading:11490157-Ribonucleases,
pubmed-meshheading:11490157-Staphylococcus aureus
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pubmed:year |
2001
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pubmed:articleTitle |
Expression and purification of recombinant rat eosinophil-associated ribonucleases, homologues of human eosinophil cationic protein and eosinophil-derived neurotoxin, and their characterization.
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pubmed:affiliation |
Laboratory of Pathophysiological Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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