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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1975-11-6
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pubmed:abstractText |
The internalization of virulent Chlamydia psittaci 6BC particles by wandering mononuclear phagocytes in the peritoneal cavity of intraperitoneally inoculated mice occurred asynchronously, i.e., fragile reticulate bodies (RB) appeared to be more readily phagocytized than the rigid elementary bodies (EB). Early damage of mononuclear phagocytes occurred after internalization of chlamydiae. This was followed by a decreased uptake of particles, and may explain the relatively long persistence (up to 6 h after inoculation) of free, extracellular, "swollen", and RB-like particles. Internalized particles within phagolysosomes showed varying degrees of disintegration. The subsequent influx of polymorphonuclear phagocytes and monocytes into the inflammed peritoneal cavity may explain the rapid disappearance of chlamydiae and their antigens from the peritoneal fluid. The alteration in ultrastructure of peritoneal cells and chlamydial parasites during the inflammatory process are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-4166
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
945-53
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:1148946-Animals,
pubmed-meshheading:1148946-Ascitic Fluid,
pubmed-meshheading:1148946-Chlamydia,
pubmed-meshheading:1148946-Humans,
pubmed-meshheading:1148946-Lysosomes,
pubmed-meshheading:1148946-Microscopy, Electron,
pubmed-meshheading:1148946-Phagocytes,
pubmed-meshheading:1148946-Phagocytosis,
pubmed-meshheading:1148946-Psittacosis,
pubmed-meshheading:1148946-Virulence
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pubmed:year |
1975
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pubmed:articleTitle |
Electron microscopy of the in vivo internalization of virulent Chlamydia psittaci 6BC strain.
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pubmed:publicationType |
Journal Article
|