Linked Life Data

1148390

Source:http://linkedlifedata.com/resource/pubmed/id/1148390

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1975-11-1
pubmed:abstractText
The role of the several pathways of complement activation in mediating a number of the biologic activities of complement has been examined in an animal model, the C4-deficient guinea pig. It has been shown that the presence of an intact classic pathway (C1, 4, 2) is requisite for damage of antibody-sensitized mammalian cell membranes and for the development of thrombocytopenia and the hypercoagulable state following in vivo endotoxin administration. Both the classic and alternate pathways participate in defense against the lethal effects of endotoxin, in opsonization and lysis of bacteria and in mediation of the events of inflammation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0547-6844
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
567-70
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Studies of the biologic effects of selective C4 deficiency.
pubmed:publicationType
Journal Article