Linked Life Data

11481579

Source:http://linkedlifedata.com/resource/pubmed/id/11481579

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2001-8-1
pubmed:abstractText
In sarcoidosis, serum ACE is widely recognised as a marker of disease activity. Since 1990 a deletion-/insertion polymorphism of the ACE gene is known and a correlation between the genotypes of this polymorphism and serum ACE levels has been observed. Homzygotes for the deletion allele (DD) have the highest levels and homozygotes for the insertion allele (II) the lowest. Heterozygote (DI) persons show intermediate levels. The extent of this influence varies in populations of different ethnic origin. In a large cohort of healthy individuals from North of Germany, genotype-based normal ranges for serum ACE were determined for the population of Germany for the first time.
pubmed:commentsCorrections
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0934-8387
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
326-32
pubmed:dateRevised
2009-4-7
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
[Corrected normal values for serum ACE by genotyping the deletion-/insertion-polymorphism of the ACE gene].
pubmed:affiliation
Forschungszentrum Borstel, Medizinische Klinik. brup@fz-borstel.de
pubmed:publicationType
Journal Article, English Abstract