Source:http://linkedlifedata.com/resource/pubmed/id/11477624
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-7-30
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pubmed:abstractText |
Rapid volumetric magnetic resonance spectroscopic imaging (MRSI) is potentially of great relevance to the diagnosis and treatment of focal cerebral diseases such as cancer and epilepsy. A strategy for volumetric multishot echo-planar spectroscopic imaging (MEPSI) is described which allows whole-brain metabolite mapping in approximately 20 min. A multishot trajectory is used in both the spatial and temporal domains which reduces the accumulated phase during each echo train and tolerates conventional Fourier reconstruction without regridding. Also described is a generalized correction for phase discontinuities arising from the multishot acquisition of the time domain, which is independent of the spatial k-space trajectory and is therefore also applicable to multishot spiral MRSI. Whole-brain, lipid-suppressed MEPSI data were acquired from five normal subjects. The mean signal-to-noise ratios (SNRs) (+/-SE) for the n-acetylaspartate (NAA), choline (Cho), and creatine (Cr) maps across all subjects were 21.3 +/- 1.8, 11.7 +/- 0.6, and 9.2 +/- 0.6, respectively, with a computed voxel size of 2.33 ml.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0740-3194
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
219-27
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11477624-Algorithms,
pubmed-meshheading:11477624-Aspartic Acid,
pubmed-meshheading:11477624-Brain,
pubmed-meshheading:11477624-Brain Mapping,
pubmed-meshheading:11477624-Choline,
pubmed-meshheading:11477624-Creatine,
pubmed-meshheading:11477624-Echo-Planar Imaging,
pubmed-meshheading:11477624-Feasibility Studies,
pubmed-meshheading:11477624-Phantoms, Imaging,
pubmed-meshheading:11477624-Signal Processing, Computer-Assisted
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pubmed:year |
2001
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pubmed:articleTitle |
Volumetric multishot echo-planar spectroscopic imaging.
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pubmed:affiliation |
Division of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, USA. mtyszka@coh.org
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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