Source:http://linkedlifedata.com/resource/pubmed/id/11476987
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2001-7-30
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pubmed:abstractText |
E-cadherin and its adhesion complex play an essential role in the adhesion of breast cancer cells and tissues. Members of the complex, such as beta-catenin, act as regulators on cell adhesion, and are involved in cell signalling and transcription regulation. The adhesion complex is a known structure in the control of tumour progression and metastasis. Recent years have seen a rapid expansion in the understanding of the biology and clinical relevance of the complex in breast cancer. The current article summarises recent progresses in the molecular/cellular biology of E-cadherin and its complex and the clinical, diagnostic, prognostic, and therapeutic value of this complex in breast cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0960-7404
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
151-71
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:11476987-Breast Neoplasms,
pubmed-meshheading:11476987-Cadherins,
pubmed-meshheading:11476987-Cell Adhesion,
pubmed-meshheading:11476987-Cell Communication,
pubmed-meshheading:11476987-Female,
pubmed-meshheading:11476987-Humans,
pubmed-meshheading:11476987-Mutation,
pubmed-meshheading:11476987-Signal Transduction
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pubmed:year |
2000
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pubmed:articleTitle |
E-cadherin complex and its abnormalities in human breast cancer.
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pubmed:affiliation |
Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, Wales CF14 4XN, UK. jiangw@cf.ac.uk
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pubmed:publicationType |
Journal Article,
Review
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