Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-7-27
pubmed:abstractText
The novel serine-threonine kinase Akt is a critical enzyme in cell survival. We investigated the roles of the Akt pathway and apoptotic signals in (1) Madin-Darby canine kidney (MDCK) cells in a hyperosmotic condition in vitro and (2) in the inner medulla of dehydrated rat in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/2-(4-morpholinyl)-8-phenyl-4H-1-benz..., http://linkedlifedata.com/resource/pubmed/chemical/Akt1 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Androstadienes, http://linkedlifedata.com/resource/pubmed/chemical/Casp3 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3, http://linkedlifedata.com/resource/pubmed/chemical/Caspases, http://linkedlifedata.com/resource/pubmed/chemical/Chromones, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Morpholines, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt, http://linkedlifedata.com/resource/pubmed/chemical/wortmannin
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0085-2538
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
553-67
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:11473638-Androstadienes, pubmed-meshheading:11473638-Animals, pubmed-meshheading:11473638-Apoptosis, pubmed-meshheading:11473638-Caspase 3, pubmed-meshheading:11473638-Caspases, pubmed-meshheading:11473638-Chromones, pubmed-meshheading:11473638-Dehydration, pubmed-meshheading:11473638-Enzyme Inhibitors, pubmed-meshheading:11473638-Kidney Medulla, pubmed-meshheading:11473638-Kidney Tubules, pubmed-meshheading:11473638-LLC-PK1 Cells, pubmed-meshheading:11473638-Male, pubmed-meshheading:11473638-Morpholines, pubmed-meshheading:11473638-Mutagenesis, pubmed-meshheading:11473638-Osmotic Pressure, pubmed-meshheading:11473638-Phosphatidylinositol 3-Kinases, pubmed-meshheading:11473638-Phosphorylation, pubmed-meshheading:11473638-Protein-Serine-Threonine Kinases, pubmed-meshheading:11473638-Proto-Oncogene Proteins, pubmed-meshheading:11473638-Proto-Oncogene Proteins c-akt, pubmed-meshheading:11473638-Rats, pubmed-meshheading:11473638-Rats, Sprague-Dawley, pubmed-meshheading:11473638-Swine, pubmed-meshheading:11473638-Transfection, pubmed-meshheading:11473638-Water Deprivation, pubmed-meshheading:11473638-Water-Electrolyte Balance
pubmed:year
2001
pubmed:articleTitle
Hyperosmolality activates Akt and regulates apoptosis in renal tubular cells.
pubmed:affiliation
Homeostasis Medicine and Nephrology, Tokyo Medical and Dental University, Tokyo, Japan. yterada.kid@tmd.ac.jp
pubmed:publicationType
Journal Article