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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-7-24
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pubmed:abstractText |
Models of immunodeficient mice reconstituted with a competent human immune system would represent an invaluable tool for the study of transplantation immunobiology allergy, autoimmunity, and infectious diseases. Severe combined immune deficiency (scid) mice can be successfully reconstituted with human peripheral blood lymphocytes (PBLs), but rates and levels of engraftment are poor. New strains of mice with diverse immunodeficiencies have been recently characterized or developed, which might prove to be advantageous for in vivo studies of human immune reactivity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-40
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11468548-Animals,
pubmed-meshheading:11468548-Antibodies, Heterophile,
pubmed-meshheading:11468548-Antigens, CD3,
pubmed-meshheading:11468548-Bone Marrow,
pubmed-meshheading:11468548-Graft vs Host Disease,
pubmed-meshheading:11468548-Humans,
pubmed-meshheading:11468548-Immunoglobulins,
pubmed-meshheading:11468548-Kinetics,
pubmed-meshheading:11468548-Lymphocyte Transfusion,
pubmed-meshheading:11468548-Lymphocytes,
pubmed-meshheading:11468548-Mice,
pubmed-meshheading:11468548-Mice, Inbred C57BL,
pubmed-meshheading:11468548-Mice, Inbred NOD,
pubmed-meshheading:11468548-Mice, SCID,
pubmed-meshheading:11468548-Peritoneum,
pubmed-meshheading:11468548-Phenotype,
pubmed-meshheading:11468548-Severe Combined Immunodeficiency,
pubmed-meshheading:11468548-Spleen,
pubmed-meshheading:11468548-Survival Analysis,
pubmed-meshheading:11468548-T-Lymphocytes
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pubmed:year |
2001
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pubmed:articleTitle |
Patterns of engraftment in different strains of immunodeficient mice reconstituted with human peripheral blood lymphocytes.
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pubmed:affiliation |
Diabetes Research Institute, University of Miami, FL 33136, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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