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11468204
Source:
http://linkedlifedata.com/resource/pubmed/id/11468204
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Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0020542
,
umls-concept:C0529793
pubmed:issue
4
pubmed:dateCreated
2001-7-24
pubmed:abstractText
This study investigated the effect of the phosphodiesterase 5 inhibitor sildenafil on the pulmonary vascular response to hypoxia in humans and mice.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/0147763
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic GMP
,
http://linkedlifedata.com/resource/pubmed/chemical/NOS3 protein, human
,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase
,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II
,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III
,
http://linkedlifedata.com/resource/pubmed/chemical/Nos3 protein, mouse
,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphodiesterase Inhibitors
,
http://linkedlifedata.com/resource/pubmed/chemical/Piperazines
,
http://linkedlifedata.com/resource/pubmed/chemical/Purines
,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfones
,
http://linkedlifedata.com/resource/pubmed/chemical/sildenafil
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1524-4539
pubmed:author
pubmed-author:AldashevAA
,
pubmed-author:KojonazarovBB
,
pubmed-author:MaripovAA
,
pubmed-author:MasonN ANA
,
pubmed-author:MirrakhimovM MMM
,
pubmed-author:MorrellN WNW
,
pubmed-author:SadykovAA
,
pubmed-author:WilkinsM RMR
,
pubmed-author:ZhaoLL
pubmed:issnType
Electronic
pubmed:day
24
pubmed:volume
104
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
424-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:11468204-Adolescent
,
pubmed-meshheading:11468204-Adult
,
pubmed-meshheading:11468204-Animals
,
pubmed-meshheading:11468204-Anoxia
,
pubmed-meshheading:11468204-Cyclic GMP
,
pubmed-meshheading:11468204-Double-Blind Method
,
pubmed-meshheading:11468204-Genotype
,
pubmed-meshheading:11468204-Heart Ventricles
,
pubmed-meshheading:11468204-Humans
,
pubmed-meshheading:11468204-Hypertension, Pulmonary
,
pubmed-meshheading:11468204-Hypertrophy
,
pubmed-meshheading:11468204-Lung
,
pubmed-meshheading:11468204-Mice
,
pubmed-meshheading:11468204-Mice, Inbred C57BL
,
pubmed-meshheading:11468204-Mice, Knockout
,
pubmed-meshheading:11468204-Nitric Oxide Synthase
,
pubmed-meshheading:11468204-Nitric Oxide Synthase Type II
,
pubmed-meshheading:11468204-Nitric Oxide Synthase Type III
,
pubmed-meshheading:11468204-Phosphodiesterase Inhibitors
,
pubmed-meshheading:11468204-Piperazines
,
pubmed-meshheading:11468204-Pulmonary Artery
,
pubmed-meshheading:11468204-Purines
,
pubmed-meshheading:11468204-Sulfones
,
pubmed-meshheading:11468204-Ventricular Function, Right
pubmed:year
2001
pubmed:articleTitle
Sildenafil inhibits hypoxia-induced pulmonary hypertension.
pubmed:affiliation
Section on Clinical Pharmacology, Imperial College School of Medicine, Hammersmith Hospital, London, UK.
pubmed:publicationType
Journal Article
,
Clinical Trial
,
In Vitro
,
Randomized Controlled Trial
,
Research Support, Non-U.S. Gov't