rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2001-7-20
|
pubmed:abstractText |
A newly approved oral fluoropyrimidine, TS-1, is a dihydropyrimide dehydrogenase (DPD)-inhibiting fluoropyrimidine (DIF) drug. We describe a case of interstitial pneumonia probably caused by TS-1. A peripheral blood lymphocytes stimulating test (DLST) with TS-1 demonstrated a substantial positive reaction. So far only three cases of TS-1-induced interstitial pneumonia have been reported but the relationship between interstitial pneumonia and TS-1 was demonstrated only in this case. Considering that interstitial pneumonia has also been reported with 5-FU, it is necessary in the future to clarify which component of this drug is directly related to interstitial pneumonia.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0368-2811
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
31
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
284-6
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:11463808-Adenocarcinoma,
pubmed-meshheading:11463808-Aged,
pubmed-meshheading:11463808-Antimetabolites, Antineoplastic,
pubmed-meshheading:11463808-Drug Combinations,
pubmed-meshheading:11463808-Humans,
pubmed-meshheading:11463808-Lung Diseases, Interstitial,
pubmed-meshheading:11463808-Male,
pubmed-meshheading:11463808-Oxonic Acid,
pubmed-meshheading:11463808-Pyridines,
pubmed-meshheading:11463808-Stomach Neoplasms,
pubmed-meshheading:11463808-Tegafur
|
pubmed:year |
2001
|
pubmed:articleTitle |
Interstitial pneumonia possibly due to a novel anticancer drug, TS-1: first case report.
|
pubmed:affiliation |
First Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Case Reports
|