Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-7-17
pubmed:abstractText
Heavy physical exercise may cause gastrointestinal signs and symptoms, and, although splanchnic blood flow may decrease through redistribution by more than 50%, it is unclear whether these signs and symptoms relate to gastrointestinal ischemia. In 10 healthy volunteers, we studied the effect of exercise on gastric mucosal perfusion adequacy using air tonometry. Two relatively short (10 min) exercise stages were conducted on a cycle ergometer, aiming for 80 and 100% of maximum heart rate, respectively. The intragastric-arterial PCO(2) gradient (Delta PCO(2)) was elevated by 1.1 +/- 1.0 kPa over baseline values (-0.1 +/- 0.3 kPa) only after maximal exercise (P < 0.001). Delta PCO(2) positively correlated with the arterial lactate level taken as an index of exercise intensity (Spearman's rank test: r = 0.76, P < 0.0001). By bilinear regression analysis, a lactate level of 12 mmol/l, above which a sharp rise in the Delta PCO(2) occurred, was calculated. We conclude that, in healthy volunteers with normal splanchnic vasculature, gastric ischemia may develop during maximal exercise as judged from intragastric PCO(2) tonometry.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
8750-7587
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
866-71
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:11457804-Adult, pubmed-meshheading:11457804-Carbon Dioxide, pubmed-meshheading:11457804-Exercise, pubmed-meshheading:11457804-Female, pubmed-meshheading:11457804-Gastric Mucosa, pubmed-meshheading:11457804-Heart Rate, pubmed-meshheading:11457804-Humans, pubmed-meshheading:11457804-Ischemia, pubmed-meshheading:11457804-Lactates, pubmed-meshheading:11457804-Male, pubmed-meshheading:11457804-Manometry, pubmed-meshheading:11457804-Partial Pressure, pubmed-meshheading:11457804-Physical Exertion, pubmed-meshheading:11457804-Reference Values, pubmed-meshheading:11457804-Regression Analysis, pubmed-meshheading:11457804-Respiratory Mechanics, pubmed-meshheading:11457804-Rest, pubmed-meshheading:11457804-Splanchnic Circulation, pubmed-meshheading:11457804-Stomach, pubmed-meshheading:11457804-Time Factors
pubmed:year
2001
pubmed:articleTitle
Exercise induces gastric ischemia in healthy volunteers: a tonometry study.
pubmed:affiliation
Department of Internal Medicine and Gastroenterology, Medisch Spectrum Twente, Enschede, The Netherlands.
pubmed:publicationType
Journal Article