11454468

Source:http://linkedlifedata.com/resource/pubmed/id/11454468

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017890, umls-concept:C0243144, umls-concept:C0268563, umls-concept:C1880355, umls-concept:C1999216
pubmed:issue	15
pubmed:dateCreated	2001-7-16
pubmed:abstractText	The discovery of Org 24598, one of the first potent and selective inhibitors of the glycine transporter is discussed. In vitro structure-activity relationships (SARs) data for interaction of a ligand with this system is discussed.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Amino Acid Transport Systems..., http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins, http://linkedlifedata.com/resource/pubmed/chemical/GABA Plasma Membrane Transport..., http://linkedlifedata.com/resource/pubmed/chemical/Glycine, http://linkedlifedata.com/resource/pubmed/chemical/Glycine Plasma Membrane Transport..., http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Transport Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Norepinephrine Plasma Membrane..., http://linkedlifedata.com/resource/pubmed/chemical/Organic Anion Transporters, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Glycine, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, N-Methyl-D-Aspartate, http://linkedlifedata.com/resource/pubmed/chemical/Slc6a2 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Symporters
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	0960-894X
pubmed:author	pubmed-author:BrownAA, pubmed-author:CarlyleII, pubmed-author:ClarkJJ, pubmed-author:GibsonSS, pubmed-author:HamiltonWW, pubmed-author:McEachenSS, pubmed-author:McGarryGG, pubmed-author:SCHJJ, pubmed-author:ThoreJJ, pubmed-author:WalkerGG
pubmed:issnType	Print
pubmed:day	6
pubmed:volume	11
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2007-9
pubmed:dateRevised	2006-11-20
pubmed:meshHeading	pubmed-meshheading:11454468-Amino Acid Transport Systems, Neutral, pubmed-meshheading:11454468-Animals, pubmed-meshheading:11454468-Brain, pubmed-meshheading:11454468-Carrier Proteins, pubmed-meshheading:11454468-GABA Plasma Membrane Transport Proteins, pubmed-meshheading:11454468-Glycine, pubmed-meshheading:11454468-Glycine Plasma Membrane Transport Proteins, pubmed-meshheading:11454468-Membrane Proteins, pubmed-meshheading:11454468-Membrane Transport Proteins, pubmed-meshheading:11454468-Norepinephrine Plasma Membrane Transport Proteins, pubmed-meshheading:11454468-Organic Anion Transporters, pubmed-meshheading:11454468-Radioligand Assay, pubmed-meshheading:11454468-Rats, pubmed-meshheading:11454468-Receptors, Glycine, pubmed-meshheading:11454468-Receptors, N-Methyl-D-Aspartate, pubmed-meshheading:11454468-Sensitivity and Specificity, pubmed-meshheading:11454468-Spine, pubmed-meshheading:11454468-Structure-Activity Relationship, pubmed-meshheading:11454468-Symporters
pubmed:year	2001
pubmed:articleTitle	Discovery and SAR of org 24598-a selective glycine uptake inhibitor.
pubmed:affiliation	Department of Medicinal Chemistry, Organon Research and Development Group, Newhouse, Lanarkshire ML1 5SH, Scotland, UK.
pubmed:publicationType	Journal Article