Linked Life Data

11452721

Source:http://linkedlifedata.com/resource/pubmed/id/11452721

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2001-7-16
pubmed:abstractText
There is an extensive literature supporting the use of rCBF as a surrogate marker of local neuronal activity. This provides a strong physiologic rationale for using PET measurements of rCBF to study the effects of drugs acting on the brain. The ability to perform multiple brief measurements of rCBF with [15O]water in a single study session makes possible a wide variety of experimental designs. Numerous investigators have successfully applied the method to study a wide variety of centrally acting drugs. In summary, then, the answer to the question, "Can [15O]water be used to evaluate drugs?" is a definitive yes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0091-2700
pubmed:author
pubmed:issnType
Print
pubmed:volume
Suppl
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11S-20S
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Can [15O]water be used to evaluate drugs?
pubmed:affiliation
PET Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
pubmed:publicationType
Journal Article, Review