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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-7-13
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pubmed:abstractText |
A number of 3-O-[2'-hydroxy-3'-N,N-aminopropan-1'-yl]-alpha-D-glucofuranoses were synthesised by regioselective oxirane ring opening in compound 2 with different secondary amines followed by selective deacetalisation. All the compounds were tested for their immunomodulatory potential in vitro; seven of them expressed significant immunostimulant activity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0223-5234
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
435-45
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11451532-Adjuvants, Immunologic,
pubmed-meshheading:11451532-Animals,
pubmed-meshheading:11451532-Chromatography, Thin Layer,
pubmed-meshheading:11451532-Disaccharides,
pubmed-meshheading:11451532-Drug Design,
pubmed-meshheading:11451532-Glucose,
pubmed-meshheading:11451532-Lymphocyte Activation,
pubmed-meshheading:11451532-Lymphocytes,
pubmed-meshheading:11451532-Mice,
pubmed-meshheading:11451532-Spectroscopy, Near-Infrared,
pubmed-meshheading:11451532-Spleen,
pubmed-meshheading:11451532-Structure-Activity Relationship
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|
pubmed:year |
2001
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|
pubmed:articleTitle |
Syntheses and immunomodulatory activity of 3-O-[2'-hydroxy-3'-N,N-disubstituted aminopropan-1'-yl]-alpha-D-glucofuranoses.
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pubmed:affiliation |
Division of Medicinal Chemistry, Central Drug Research Institute, Lucknow 226001, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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