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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2001-7-13
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pubmed:abstractText |
Digital fluorescence imaging techniques were employed to monitor changes in the cytoplasmic Ca2+ concentration and mitochondrial potential in fura-2 AM or rhodamine-123 loaded individual cerebellar granule cells during and following the Glu exposure. The data obtained suggests that the MD-induced blockade of the mitochondrial Ca2+ uptake and a reversal of the mitochondrial ATP-synthase play a critical role in the mechanism of the glutamate-induced disorder of neuronal Ca2+ homeostasis.
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pubmed:language |
rus
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphatases,
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Dinitrophenols,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorescent Dyes,
http://linkedlifedata.com/resource/pubmed/chemical/Fura-2,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Oligomycins,
http://linkedlifedata.com/resource/pubmed/chemical/Rhodamine 123,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Cyanide
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0869-8139
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
459-67
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11449973-Adenosine Triphosphatases,
pubmed-meshheading:11449973-Adenosine Triphosphate,
pubmed-meshheading:11449973-Animals,
pubmed-meshheading:11449973-Calcium,
pubmed-meshheading:11449973-Cells, Cultured,
pubmed-meshheading:11449973-Dinitrophenols,
pubmed-meshheading:11449973-Enzyme Inhibitors,
pubmed-meshheading:11449973-Fluorescent Dyes,
pubmed-meshheading:11449973-Fura-2,
pubmed-meshheading:11449973-Glutamic Acid,
pubmed-meshheading:11449973-Homeostasis,
pubmed-meshheading:11449973-Membrane Potentials,
pubmed-meshheading:11449973-Mitochondria,
pubmed-meshheading:11449973-Neurons,
pubmed-meshheading:11449973-Oligomycins,
pubmed-meshheading:11449973-Rats,
pubmed-meshheading:11449973-Rats, Wistar,
pubmed-meshheading:11449973-Rhodamine 123,
pubmed-meshheading:11449973-Sodium Cyanide
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pubmed:year |
2001
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pubmed:articleTitle |
[The leading role of mitochondrial depolarization in the mechanism of glutamate-induced disorder in Ca(2+)-homeostasis].
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pubmed:affiliation |
Institute of General Pathology and Pathophysiology, Russian Acad. Med. Sci., Baltiyskaya St., 8, Moscow 125315, Russia.
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pubmed:publicationType |
Journal Article,
English Abstract
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