|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7 Suppl
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|
pubmed:dateCreated |
2001-7-10
|
|
pubmed:abstractText |
In the pathogenesis of disseminated intravascular coagulation, dysfunctional natural anticoagulant pathways appear to play a pivotal role. In this article, we will address the mechanisms that contribute to this defect in the regulation of coagulation activation. Furthermore, we will explore the experimental and clinical evidence that restoration of these anticoagulant pathways results in clinical improvement.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0090-3493
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
29
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
S90-4
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:11445740-Animals,
pubmed-meshheading:11445740-Anticoagulants,
pubmed-meshheading:11445740-Cytokines,
pubmed-meshheading:11445740-Disease Models, Animal,
pubmed-meshheading:11445740-Disseminated Intravascular Coagulation,
pubmed-meshheading:11445740-Humans,
pubmed-meshheading:11445740-Multiple Organ Failure,
pubmed-meshheading:11445740-Protein C,
pubmed-meshheading:11445740-Sepsis,
pubmed-meshheading:11445740-Thrombin,
pubmed-meshheading:11445740-Thromboplastin,
pubmed-meshheading:11445740-Treatment Outcome
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Rationale for restoration of physiological anticoagulant pathways in patients with sepsis and disseminated intravascular coagulation.
|
|
pubmed:affiliation |
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
|
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|
