pubmed-article:11445278 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11445278 | lifeskim:mentions | umls-concept:C0012655 | lld:lifeskim |
pubmed-article:11445278 | lifeskim:mentions | umls-concept:C0036572 | lld:lifeskim |
pubmed-article:11445278 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
pubmed-article:11445278 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:11445278 | lifeskim:mentions | umls-concept:C0021358 | lld:lifeskim |
pubmed-article:11445278 | lifeskim:mentions | umls-concept:C0035696 | lld:lifeskim |
pubmed-article:11445278 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
pubmed-article:11445278 | lifeskim:mentions | umls-concept:C1422213 | lld:lifeskim |
pubmed-article:11445278 | lifeskim:mentions | umls-concept:C0598850 | lld:lifeskim |
pubmed-article:11445278 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:11445278 | pubmed:dateCreated | 2001-7-10 | lld:pubmed |
pubmed-article:11445278 | pubmed:abstractText | Cardiac arrest and resuscitation were used to induce brain damage and susceptibility to sound-triggered seizures in Sprague-Dawley rats. Glucose preloading was used to vary seizure susceptibility. Because loop diuretics can block these seizures, we investigated changes in KCC2, a potassium-chloride cotransporter, in the inferior colliculus - the origin of the seizures. Using polymerase chain reaction (PCR), we found that collicular KCC2 mRNA levels covaried with seizure susceptibility in these animals. Using quantitative PCR, we found that a fivefold increase in collicular KCC2 mRNA levels was associated with a doubling of seizure incidence. A hypothesis linking KCC2 activity to seizure susceptibility is presented. | lld:pubmed |
pubmed-article:11445278 | pubmed:language | eng | lld:pubmed |
pubmed-article:11445278 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11445278 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11445278 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11445278 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11445278 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11445278 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11445278 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11445278 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11445278 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11445278 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11445278 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11445278 | pubmed:month | Jul | lld:pubmed |
pubmed-article:11445278 | pubmed:issn | 0304-3940 | lld:pubmed |
pubmed-article:11445278 | pubmed:author | pubmed-author:SchurrAA | lld:pubmed |
pubmed-article:11445278 | pubmed:author | pubmed-author:ReidK HKH | lld:pubmed |
pubmed-article:11445278 | pubmed:author | pubmed-author:LiG YGY | lld:pubmed |
pubmed-article:11445278 | pubmed:author | pubmed-author:CooneyL DLD | lld:pubmed |
pubmed-article:11445278 | pubmed:author | pubmed-author:PayneR SRS | lld:pubmed |
pubmed-article:11445278 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11445278 | pubmed:day | 27 | lld:pubmed |
pubmed-article:11445278 | pubmed:volume | 308 | lld:pubmed |
pubmed-article:11445278 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11445278 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11445278 | pubmed:pagination | 29-32 | lld:pubmed |
pubmed-article:11445278 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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pubmed-article:11445278 | pubmed:year | 2001 | lld:pubmed |
pubmed-article:11445278 | pubmed:articleTitle | The mRNA level of the potassium-chloride cotransporter KCC2 covaries with seizure susceptibility in inferior colliculus of the post-ischemic audiogenic seizure-prone rat. | lld:pubmed |
pubmed-article:11445278 | pubmed:affiliation | Department of Anatomical Sciences and Neurobiology, School of Medicine, University of Louisville, Louisville, KY, USA. khreid01@louisville.edu | lld:pubmed |
pubmed-article:11445278 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11445278 | lld:pubmed |