Source:http://linkedlifedata.com/resource/pubmed/id/11443226
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2001-7-9
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pubmed:abstractText |
The naturally occurring polyamines putrescine, spermidine, and spermine are involved in signal transduction. This has been demonstrated by using inhibitors for polyamine biosynthesis (such as alpha-difluoromethylornithine) or adding polyamines to cultured cells. Different polyamines, preferentially activated protein kinases (tyrosine kinases and MAP kinases), stimulated the expression of nuclear protooncogenes (myc, jun, and fos).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0886-1714
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
106-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11443226-Animals,
pubmed-meshheading:11443226-Cell Division,
pubmed-meshheading:11443226-Cell Nucleus,
pubmed-meshheading:11443226-Cell Physiological Phenomena,
pubmed-meshheading:11443226-Gene Expression,
pubmed-meshheading:11443226-Oncogenes,
pubmed-meshheading:11443226-Polyamines,
pubmed-meshheading:11443226-Signal Transduction
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pubmed:year |
2001
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pubmed:articleTitle |
Polyamines: new cues in cellular signal transduction.
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pubmed:affiliation |
Department of Molecular Biology, Hebrew University-Hadassah Medical School, 91120 Jerusalem, Israel.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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