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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
2001-7-9
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pubmed:abstractText |
A hospital-based prospective study of 99 patients with community-acquired pneumonia (CAP) was carried out in Kampala, Uganda. We evaluated microbiological etiologies, clinical features and effectiveness of short-term parenteral ampicillin followed by oral amoxicillin for these patients in relation to HIV-status. We demonstrated a very high prevalence (75%) of HIV-1 infection. No significant difference was observed with respect to age, gender, prior antibiotic usage, symptoms, laboratory data or bacterial etiology between HIV-1-infected and HIV-uninfected CAP patients. Most strains of Streptococcus pneumoniae (n = 19) and Haemophilus influenzae (n = 8) isolated from HIV-1-infected patients were penicillin-resistant (95%) and beta-lactamase producing (75%) strains, respectively. A high percentage of good clinical response was found in both HIV-1-infected (81%) and HIV-uninfected (86%) among 39 patients with CAP due to a defined bacterial pathogen. These data support the use of short-term parenteral ampicillin for patients with bacterial CAP irrespective of HIV-status.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0002-9637
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pubmed:author |
pubmed-author:AhmedKK,
pubmed-author:AitaKK,
pubmed-author:AmanoHH,
pubmed-author:JolobaMM,
pubmed-author:MubiruFF,
pubmed-author:MugerwaRR,
pubmed-author:NagatakeTT,
pubmed-author:NalwogaHH,
pubmed-author:OishiKK,
pubmed-author:OmbasiPP,
pubmed-author:ShimadaMM,
pubmed-author:TakahashiHH,
pubmed-author:WatanabeKK,
pubmed-author:YoshimineHH
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
172-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11442214-Administration, Oral,
pubmed-meshheading:11442214-Adult,
pubmed-meshheading:11442214-Amoxicillin,
pubmed-meshheading:11442214-Ampicillin,
pubmed-meshheading:11442214-Community-Acquired Infections,
pubmed-meshheading:11442214-Drug Administration Schedule,
pubmed-meshheading:11442214-Drug Resistance, Microbial,
pubmed-meshheading:11442214-Female,
pubmed-meshheading:11442214-HIV Infections,
pubmed-meshheading:11442214-HIV-1,
pubmed-meshheading:11442214-Haemophilus influenzae,
pubmed-meshheading:11442214-Humans,
pubmed-meshheading:11442214-Infusions, Intravenous,
pubmed-meshheading:11442214-Male,
pubmed-meshheading:11442214-Microbial Sensitivity Tests,
pubmed-meshheading:11442214-Penicillins,
pubmed-meshheading:11442214-Pneumonia, Bacterial,
pubmed-meshheading:11442214-Prevalence,
pubmed-meshheading:11442214-Prospective Studies,
pubmed-meshheading:11442214-Streptococcus pneumoniae,
pubmed-meshheading:11442214-Treatment Outcome,
pubmed-meshheading:11442214-Uganda
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pubmed:articleTitle |
Community-acquired pneumonia in Ugandan adults: short-term parenteral ampicillin therapy for bacterial pneumonia.
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pubmed:affiliation |
Department of Internal Medicine and Information and Reference Center, Institute of Tropical Medicine, Nagasaki University, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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